Axis 1. The central role of episodic
memory impairments in psychosis
Our research laboratory have contributed significantly to this literature by combining cognitive neuroscientific techniques such as brain imaging to answer clinically relevant questions. We have observed that people with schizophrenia exhibit a selective memory deficit for relational memory (1) and this deficit relates to abnormalities in the hippocampo-prefrontal system (2). This work has examined the whole continuum of psychosis from clinical high risk (3), early psychosis (4) and enduring schizophrenia (5). Importantly, we have shown that such memory impairments selectively and negatively influence clinical (6) and functional (7) trajectories.
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References
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(1) See Lepage et al., 2015 for a review
(2) See Achim et al, 2005a; 2005b; Guimond et al., 2017; Hawco et al., 2013; 2015 Luck et al., 2016
(4) See Achim et al., 2007; Lepage et al., 2006; 2014; Luck et al., 2009; 2014
(5) See Guimond et al., 2016; 2017; Sauvé et al., 2019
(6) Bodnar et al., 2008; 2010; 2011; 2012
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